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On September 26, UCLA researcher reported the final results of a study, which indicated that Asians who will be struggling with alcoholism will manage to benefit especially from naltrexone, certainly one of three medications licensed by the U.S. Food and Drug Administration (FDA) for your treatment of alcoholism. Recent research has found out that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent possess a particular mutation which makes them prone to benefit from naltrexone, compared with about 20% of Caucasians and fewer than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director in the UCLA Addictions Laboratory. The findings are currently available online ( within the journal Neuropsychopharmacology and will be published in the upcoming print edition of the journal. Using two separate drugs to shed weight can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the those who go through it you need to err along the side of caution and allow FDA do its job and demand some study be done so the public knows the side effects and hazards of the medications before we take them. Keep in mind that drug companies have been in business to generate money and that they would say almost anything to keep people on their own medications. Researchers discovered that participants investing in this drug for the year, dropped a few pounds within a month and have kept the load off through the 56 weeks with the study. Contrave is a combination with the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs which are made up of several active ingredient, which might make them more efficient and safer. Combo-pilling could be the newest fad or better yet the newest to come under scrutiny and so it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular will be the fact that since right now there are not any long term prescription weightloss pills that have been authorized by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be approved by the FDA. Seizures are a side effect with Contrave and must not be taken in people who have seizure disorders. The drug can also raise blood pressure and heart rate, and must not be used in those with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure levels and heart rate and must 't be used in patients with uncontrolled high blood pressure level, as well as by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients with a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients to the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking. The most common negative effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.